Enhancement in hyperthermia properties of cobalt ferrite nanoparticles by changing reaction time

Researchers at University of Kashan have recently performed a study on hyperthermia properties of cobalt ferrite (CoFe2O4) nanoparticles synthesized using a thermal decomposition method with three temperature steps. They changed the reaction time of the second step and investigated magnetic characteristics using a vibrating sample magnetometer (VSM) manufactured by MDK company. They also used first-order reversal curve (FORC) analysis by VSM of our company in order to delve into details of magnetic properties and domain state of the resulting nanoparticles. In this regard, highly superparamagnetic CoFe2O4 nanoparticles were manifested by the FORC diagram.

To evaluate hyperthermia properties (specific loss power or SLP), they used our Hyperthermia System (MDK) and achieved SLP of up to 510 W/g with increasing the reaction time from 75 to 150 min. The researchers also investigated cytotoxicity of the nanoparticles, and found cell viability values exceeding 95% after 48 h, indicating their low toxicity or bio-friendly nature. Therefore, “CoFe2O4 nanoparticles may find potential applications in targeted drug delivery and magnetic hyperthermia for treating various cancers such as colon, lung, and breast cancers. As well, they might be employed as MRI agents for specific and precise detection of cancer cells”. The results of this research have been published in the journal Materials Chemistry and Physics.

To see full paper, click here.

Leave a Reply

Your email address will not be published. Required fields are marked *